Fig. 3

Bisphenol A adverse effects on vital organs: brain (due to thyroid hormone disruptions), heart (heart failure and several heart diseases), liver (disruption of glucose and lipid metabolism, increased risk of type 2 diabetes and obesity), and kidney (interruption in leptin). Notes: CVD is cardiovascular diseases, body mass index is calculated by dividing the weight (kg) by height (m), chronic hyperinsulinaemia is a condition of excess level of insulin in the blood and usually promoted by obesity and associated with adipose dysfunction, and leptin is a hormone secreted by white adipose tissue that has an important role in the regulation of body weight; a larger amount of plasma leptin is associated with chronic kidney disease, and is thus, indirectly related to the kidney and the prevalence of obesity