Table 1 Summary of fragment and neutral loss (NL) screening from the fluorinated tail and polar head, respectively, in the study. Normal font subclasses recognized from both tail and head, bold subclasses only from headgroup, italicized subclass from tail

[SO₂N]^–

FASAAs

E-FASAs

E-FASAAs

H-FASAAs

FASAs

H-FASAs

[SO₂F]^–

PFSAi

N-Alkyl FASAAs

[SO₃]^–

FASEEs

H₂-E-PFSAs

H₂-E-PFSAs

H-PFSAs

n:2 FTSAs

H₂-E-PFSA

PFSAs

[HSO₂]^–

N-Alkyl FASAs

FASEE mono-ol

monoacids

E-FASEs

U-FASEs

E–H-FASEs

U-E-FASEs

FASEs

H-FASEs

Miscellaneous FASEs

FASAcALs

FASAcAL hydrates/ hemiacetals

[SO₂NC₂H₄O]^–

FASEE mono-ol

monoacids

E-FASEs

U-FASEs

H-E-FASEs

U-E-FASEs

FASEs

H-FASEs

Miscellaneous FASEs

[SO₂N(C₂H₄O)₂]^–

FASEEs

H-FASEEs

CO₂^a

PFCAs

U-E-PFCAs

PFdiCAs

U-PFCAs

U-E-PFCAs

PFdiCAs

U-E-PFCAs

PFdiCAs

CO₂HF^a

H-E-PFCAs

H₂-E-PFCAs

H-E-PFCAs

H-PFCAs

H-E-PFCAs

C_nH_2nCO₂^a,b

FASAAs

FASPrAs

N-Alkyl FASAAs

FASEE diacids FASEE mono-ol monoacids

E-FASAAs

H-FASAAs

X = SO₃, CONH,..^a

Miscellaneous FASAs

Miscellaneous FASEs

No prior fragments and NL from headgroup

E-PFCAs